![]() Elective versus therapeutic neck dissection in node-negative oral cancer. Pretreatment screening on distant metastases and head and neck cancer patients: validation of risk factors and influence on survival. Objective: To review the results of SLNB for patients with cSCC of the head and neck at the authors' institution. Clinical nodal stage is a significant predictor of outcome in patients with oral cavity squamous cell carcinoma and pathologically negative neck metastases: results of the international consortium for outcome research. Background: Limited data exist on sentinel lymph node biopsy (SLNB) for cutaneous squamous cell carcinoma (cSCC) of the head and neck. Methods: This prospective, cooperative group trial involved 25 institutions over a 3-year period. 2019 31(1):13-29.Īmit M, Yen TC, Liao CT, et al. Purpose: The validity of sentinel lymph node biopsy (SLNB) for T1 or T2, clinically N0, oral cancer was tested by correlation of sentinel node pathologic status with that of nodes within the completion neck dissection. 2018 68(6):394-424.Įttinger KS, Ganry L, Fernandes RP. Sentinel Lymph Node Biopsy (SLNB) is a surgical procedure used to determine the extent or stage of certain types of cancers such as melanoma, breast cancer. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. Thin serial step sectioning of sentinel lymph node biopsy specimen may not be necessary to accurately stage the neck in oral squamous cell carcinoma J Oral Maxillofac Surg. Overall, SLNB results in as favorable an oncologic prognosis for patients with cN0 oral SCC as END, while significantly lessening side effects and unnecessary surgeries.Įlective neck dissection meta-analysis oral cavity sentinel lymph node biopsy squamous cell carcinoma.īray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Patients and methods: Eligible women had squamous cell carcinoma, at least 1-mm invasion, and tumor size 2 cm and 6 cm. Fewer adverse events occurred in the SLNB arm than in the END arm (RR = 0.12 95% CI, 0.02-0.70). Purpose: To determine the safety of sentinel lymph node biopsy as a replacement for inguinal femoral lymphadenectomy in selected women with vulvar cancer. The meta-analysis, including six prospective studies, showed comparable results of the two management strategies in terms of regional recurrence (risk ratio = 0.99 95% confidence interval, 0.58-1.70), 5-year disease-free survival (RR = 0.99 95% CI, 0.87-1.11), and 5-year overall survival (RR = 1.01 95% CI, 0.90-1.13). Herein, relevant literature was systematically reviewed, and a meta-analysis was performed to evaluate the potential dividends of SLNB compared to elective neck dissection (END) for these patients. However, the role of SLNB in this scenario is debatable. Sentinel lymph node biopsy (SLNB) is an emerging strategy for managing early-stage oral squamous cell carcinoma (SCC) with a clinically N0 (cN0) neck.
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